PS-6.5 Ovarian tissue transplantation

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Fresh ovarian tissue and whole ovary transplantation.

A series of monozygotic (MZ) twin pairs discordant for premature ovarian failure presented an unusual opportunity to study ovarian transplantation. Ten MZ twin pairs requested ovarian transplantation and nine have undergone transplantation with cryopreservation of spare tissue. Eight had a fresh cortical tissue transplant, one of whom received a second frozen-thawed transplant after the first c...

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oVAriAn tissue trAnsplAntAtion: A teleologiCAl perspeCtiVe

Many female patients present with malignant and non-malignant conditions whose treatment causes infertility. Women who are diagnosed with neoplastic diseases before1 or during2 their reproductive years and undergo ootoxic therapies,3 those who undergo an oophorectomy due to non-malignant disorders,4 those of reproductive age at risk for premature menopause associated with genetic disorders, and...

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Orthotopic and heterotopic ovarian tissue transplantation

BACKGROUND Transplantation of ovarian tissue is, at present, the only clinical option available to restore fertility using cryopreserved ovarian tissue. More than 30 transplantations of cryopreserved tissue have been reported, and six babies have been born, worldwide, following this procedure. Despite these encouraging results, it is essential to optimize the procedure by improving the follicul...

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Reproductive outcome after transplantation of ovarian tissue: a systematic review.

BACKGROUND Despite interest in ovarian tissue transplantation (OTT) as a promising procedure for fertility preservation, to date, no precise data are available about its effectiveness. We systematically reviewed reproductive function after OTT for fertility preservation in women at high risk of premature ovarian failure (POF). METHODS We searched the MEDLINE, EMBASE, Cochrane Systematic Revie...

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Livebirth after orthotopic transplantation of cryopreserved ovarian tissue.

BACKGROUND The lifesaving treatment endured by cancer patients leads, in many women, to early menopause and subsequent infertility. In clinical situations for which chemotherapy needs to be started, ovarian tissue cryopreservation looks to be a promising option to restore fertility. In 1997, biopsy samples of ovarian cortex were taken from a woman with stage IV Hodgkin's lymphoma and cryopreser...

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ژورنال

عنوان ژورنال: Reproductive BioMedicine Online

سال: 2008

ISSN: 1472-6483

DOI: 10.1016/s1472-6483(10)61491-5